Febuxostat API INTERMEDIATE

(2022年07月07日)

Febuxostat
CAS NO: 144060-53-7
 
 
Items
Standards
Results

Appearance
White to yellow crystalline powder
White crystalline powder

Solubility
Freely soluble in DMF, soluble in THF, sparingly soluble in acetone, ethanol and ethyl acetate, slightly soluble in acetonitrile, very slightly soluble in methanol and practically insoluble in water
Complies

Identification
HPLC/UV
Complies

Related Substances

Total impurities:NMT1.0%
Maximum single impurity:NMT0.5%

0.20%
0.18%

Loss on drying
(Dry it at 105 in an electric air blowing dryer till a constant weight)

NMT1.0%
0.09%

Residue on lgnition
NMT0.1%
0.07%

Heavy Metal
NMT20ppm
Complies

Chlorides
NMT 0.04%
Complies

Assay(on dried basis)
NLT 98.5%
100.4%

 
we are the largest supplier of Febuxostat (pharmaceutical).
 
we can supply both API and INTERMEDIATES of Febuxostat as following:
 
161797-99-5:Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
161798-01-2: Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
160844-75-7: Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
 
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