Cardiac Marker Test

(2022年08月26日)

https://www.medical-ivd.com/products/cardiac-marker-test/

Cardiac Biomarkers List

Cardiac markers are substances that are released into the blood when the heart is damaged or stressed. Tests of these markers are used to help diagnose acute coronary syndrome (ACS) and cardiac ischemia, conditions associated with insufficient blood flow to the heart.

The main markers of myocardial injury were troponin T, troponin I, creatine kinase isoenzyme mass (CK MB) and myoglobin. Troponin is composed of three subunits.

What is Cardiac Markers Test
Cardiac markers in stable angina refer to myocardial markers that diagnose cardiac injury including myocardial infarction and myocardial minor injury, mainly including cardiac enzymes including creatine kinase (CK) and isoenzyme (CKMB), aspartate aminotransferase (GOT/AST), lactate dehydrogenase. enzyme (LDH), hydroxybutyrate dehydrogenase (HDBD); myoglobin, troponin, etc. In recent years, risk factors for predicting heart disease, especially coronary heart disease, have been used as positive cardiac markers, such as high-sensitivity C-reactive protein, peripheral blood mononuclear cell count, high-density lipoprotein to low-density lipoprotein ratio, Chlamydia pneumoniae antibodies, prothrombotic body protein, fibrinogen, etc.

Advantages Of Cardiac Marker Test
Myocardial injury markers are increasingly becoming the markers of screening, monitoring, follow-up and prognosis of myocardial injury such as MI and AMI. Myocardial projects, mature antigens, and gradually perfect antibodies.

Cardiac Markers Meaning
Myoglobin is the best early marker for myocardial injury. CTnI / cTnT was unanimously rated by the American and European Heart Association as a highly specific and sensitive diagnostic marker for acute myocardial infarction.The sensitivity and specificity of CK mbmass detection are much higher than CK-MB activity. Therefore, when cTnI or cTnT detection is not carried out, CK mbmass can be used to assist clinical diagnosis. It is close to troponin in the diagnosis of acute coronary syndrome and the evaluation of the degree of myocardial injury, as well as in sensitivity and specificity.

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