Soluble Fms-like tyrosine kinase-1 (sFlt-1)
(2024年04月19日)https://www.sekbio.com/soluble-fms-like-tyrosine-kinase-1-sflt-1.html
Soluble fms like tyrosine kinase-1 is a tyrosine kinase protein with antiangiogenic properties. A non-membrane-associated splice variant of VEGF receptor 1, sFlt-1 binds the angiogenic factors VEGF and PlGF, reducing blood vessel growth by reducing free VEGF and PlGF concentrations. Sflt 1 antibody/PLGF ratio is valuable for assessing the severity of preeclampsia and diagnosing early-onset preeclampsia and can be used to predict neonatal birth weight.
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