PHARMACEUTICAL EXCIPIENTS IN AVT

(2024年03月14日)

https://www.avt-pharma.com/products/

Common pharmaceutical excipients manufacturer AVT has been cultivating the market of high- end complex injection in China for more than ten years, and has been cooperating with domestic R&D and production companies, universities as well as research institutes on various types of complex injection for many years. Our injectable excipients pharma are widely used in marketed liposomes, fat emulsion formulations and biological formulations as well as in the research and development of these new drugs. As a reliable pharma industry excipients supplier, the quality and safety of our various types of pharmaceutical excipients are trustworthy.

TYPES OF PHARMACEUTICAL EXCIPIENTS
Biopharmaceutical Excipients
AVT strives to provide low-endotoxin excipients used in injections that meet urgent needs of biopharmaceutical development. The quality of different types of excipients in pharma conforms to USP, EP, JP standards, and has been registered in US FDA with DMF number.

Liposome Excipients
As pharma excipient manufacturer, we provide multi-species, injectable and high-purity for lipo-some drug development; our production base meets GMP requirements for pharma excipients market and can receive audits from various countries; we have a complete range of liposome excipients of drugs to meet the needs of different customers for types of excipients used in pharmaceutical industry and can provide customized pharmaceutically acceptable excipient services.

Fat Emulsion Excipients
We provide cost-effective lecithins and oleic acid excipients for the devel-opment and production of fat emulsion drugs; The production base meets GMP requirements for excipient manufacturing; product quality complies with USP, EP and JP stan-dards, all excipients are injectable excipients; We have suficient production capacity with annual output of types of excipients around 50 to 300 tons to meet your demands.

Lipid nanoparticles(LNPs)
lipid nanoparticles (LNPs), are nanoparticles composed of lipids (including cationic lipid、phospholipid、PEG-lipid and helper lipid). They are the most clinically advanced non-viral gene delivery system for Intracellular Delivery of Nucleic Acid Therapeutics. LNPs as a drug delivery vehicle were first approved in 2018 for the siRNA drug Onpattro. Currently in the spotlight as vital components of the COVID-19 mRNA vaccines (including both the Moderna and the Pfizer–BioNTech COVID-19 vaccines), LNPs play a key role in effectively protecting and transporting mRNA to cells.

WHAT IS PHARMA EXCIPIENTS MEANING IN PHARMACEUTICALS ?
In pharma excipients market, excipients in pharmacy refer to any kind of API (Active Pharmaceutical Ingredients) to be provided for clinical use, and must be made into various pharmaceutical preparations without dosage forms. In addition to the preparation of pharmaceutical preparations, some excipients that help the preparation of different functions such as molding, stabilization, increase solubility, and sustained release must also be added. These various necessities used in the manufacture and preparation of pharmaceutical preparations are called pharmaceutical preparation excipients, referred to as pharmaceutical excipients. The above is a brief introduction of the pharmaceutical excipients definition. Pharmaceutical excipients are the material basis for the existence of pharmaceutical preparations, and there is no pharmaceutical preparation without pharmaceutical excipients.

AVT LTD FEATURED PHARMACEUTICAL EXCIPIENTS LIST PDF

D(+)-Trehalose Dihydrate (For Injection) CAS No.: 6138-23-4
This product is sterile pharmaceutical grade alginate dihydrate with high glass transition temperature, low hygroscopicity and water retention, etc. Trehalose dihydrate is also heat resistant, acid resistant and extremely stable, and is the most stable molecule among natural disaccharides. Alginate has been successfully applied in medicine as a stabilizer for blood products, vaccines, cell tissues and other bioactive substances, which can not only prolong the storage time at room temperature, but also prevent the contamination of blood sources. Also alginate is widely used as a lyophilization protector for biological products. Besides, alginate is also a good choice as a lyophilization protector for liposomes.

Tromethamine (for injection) TRIS
Tromethamine tris is often used as a buffer for proteins or nucleic acids, and can also be used to prepare intermediates for surfactants, sulfur promoters, and some drugs such as phosphomycin, which are used in cosmetics, pharmaceuticals, coatings, and synthesis.

Sucrose Octasulfate Potassium Salt Cas No.: 73264 44 5
Sucrose octasulfate Potassium saltis an active substance in the body, which activates in vivo or fibroblast growth factors. It was early used in the treatment of ulcer-based drugs and later used as a novel excipient in liposome preparations.

CAS NO 57 50 1 Sucrose For Sale (For Injection)
This product is high purity sucrose low endotoxin injectable grade pharmaceutical sucrose, which is often used in the field of pharmacy as a lyophilization protectant in nano preparations and protein biologics. It acts as a low temperature protectant in the lyophilization process and a dehydration protectant in drying and dehydration, and also regulates the osmotic pressure, which is recognized as one of the most widely used and effective lyophilization protectants.

WHY CHOOSE AVT PHARMACEUTICAL EXCIPIENTS?

15 years dedicated to types of high-level pharmaceutical excipients used in injections.

Rich experience in FDA registration for pharma excipient market products.

Integration of R&D, production and marketing.

Ablility to provide customized pharma excipients products.

Product quality conforms to USP, EP, JP.

List Of Pharmaceutical Excipients And Their Uses
-Roles in a Formulation
LIST OF PHARMACEUTICAL EXCIPIENTS AND THEIR USES
Types of pharmaceutical excipients and their uses:

Forming agent,like excipients used in pharmaceutical dosage forms

Excipients meaning in pharmaceuticals can smoothen the preparation process

Improve drug stability

Improve efficacy of drugs

Reduce drug toxicity and side effects

Adjust the effect of drugs

Improve patient compliance with medication
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