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https://www.difficultpeptide.com/products/ub-amc/

Ubiquitin AMC is prepared by the C-terminal derivatization of ubiquitin with 7-amino-4-methylcoumarin.

SPECIFICATION OF UB AMC
CATU1010
Product NameUb-AMC
Purity≥95% by HPLC analysis
AppearanceLyophilized powder
UsageResearch use only
StorageShipping at room temperature.
Upon delivery aliquot.
Stored at -20°C or -80°C.
Avoid freeze/thaw cycle.
IntroductionUbiquitin-AMC is a fluorogenic substrate for a wide range of deubiquitinating enzymes (DUBs), including ubiquitin C-terminal hydrolases (UCHs) and ubiquitin-specific proteases (USPs). It is a particularly useful reagent for the study of deubiquitinating activity where detection sensitivity or continuous monitoring of activity is essential.

APPLICATION OF UB AMC
Can be used for the following applications:

1. Substrate for deubiquitinylating enzyme activity assays.

2. Identification/confirmation of enzyme deubiquitinylation activity.

3. Investigation of deconjugating enzyme-substrate specificity in comparison with alternative UBL substrates.

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