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Commonly used heparin anticoagulants are sodium, potassium, lithium and ammonium salts of heparin, among which lithium heparin additive is the best, and is often used in vacuum blood collection tubes.

Heparin lithium is a commonly used blood anticoagulant replaced on the basis of heparin sodium. It has the characteristics of minimal chelation, minimal interference to water and relatively low cation concentration. It is used in clinical biochemical and emergency biochemical examinations, chemical measurement tests., lithium heparin is the top choice of anticoagulant for measuring pH, blood gases, electrolytes, and ionized calcium.

Lithium Heparin Details

Desheng Lithium Heparin is a white amorphous powder with no odor. It is the best choice for manufacturers of heparin tubes for blood collection tubes. The regular potency is 150IU/mg. Other potency requirements(150IU/mg-200IU/mg) can also be met. Lithium heparin is often used for blood anticoagulation, providing conditions for clinical biochemical emergency examinations and hemorheology projects.

Advantages of Desheng Lithium Heparin:
The lithium heparin developed and produced by Desheng has high potency & activity and good blood anticoagulation effect;

Desheng has a professional R&D team for blood collection tube additives, which can customize product indicators for heparin lithium products, and produce heparin lithium products with high price and other indicators to meet various needs;

Desheng Lithium Heparin is stable and has good water solubility, which can meet the rapid filling and production of blood collection tubes;

Desheng is a direct manufacturer of heparin lithium, with proper cost control, and has long-term stock of heparin lithium in excess of kilograms, which can be delivered immediately and reduce procurement costs to meet the needs of bulk goods;

Desheng has 17 years of experience in R&D and production of lithium heparin, and has professional solutions for more than 90% of heparin-related problems

There is a professional foreign trade team, not only has rich export experience, but also has a very good understanding of the use and configuration of products, and can deal with the problems you encounter in procurement in a timely manner.

Application Of Lithium Heparin
Lithium heparin powder is prepared into a solvent and then sprayed in the blood collection tube in the form of spray, as a heparin anticoagulant plasma tube, which is used for serum biochemistry, immunology, drug testing, scientific research experiments, etc.;

Lithium heparin and serum separation gel can be used at the same time, and can be used as a heparin separation rubber tube. It is recommended to be used in conjunction with the blood separation gel produced by our company to obtain high-quality plasma samples for emergency biochemical project detection;

Lithium heparin can also be used for blood gas analysis, trace blood collection, etc.

Lithium Heparin Production Process
Heparin lithium is made from heparin sodium through ion exchange. After heparin sodium passes through cation exchange resin, sodium ions are exchanged with lithium ions, so that heparin sodium is converted into heparin lithium; it is then refined into heparin through alcohol precipitation, drying and other steps. Lithium products.

Crude heparin glycolysis-à Deproteinized-> Oxidative decolorization-〉resin exchange- Precipitation, Dehydration, Drying

Instructions for Lithium Heparin:
Prepare quantitative lithium heparin, volumetric flask, glass rod, washing bottle, deionized water, beaker, etc.（Pre-sterilization is required for the use of utensils）

Use an electronic balance to accurately weigh the lithium heparin powder to the nearest 1/10,000, and then put the lithium heparin powder into the beaker according to the pre-calculated usage amount.

Weigh a certain amount of deionized water and pour it into a beaker to dissolve it. Stir slowly with a glass rod while adding water, and transfer it to a volumetric flask after all dissolved

After the lithium heparin is completely dissolved, it is necessary to further adjust the volume. Use the washing bottle to slowly add deionized water along the mouth wall of the volumetric flask until the bottom of the liquid level is consistent with the scale line. Hold the bottom of the volumetric flask, carefully invert and mix 5-8 times to fully mix the lithium heparin solution

Dosage Reference Table for Lithium Heparin:

According to the requirements of Annex NC of YY0314-2007 standard, the concentration range of heparin lithium is 10-30 USP units per ml of blood sample; the range of heparin sodium and lithium concentration is 12-30 IU per ml of blood sample, and the anticoagulation of peripheral blood is 8IU-10IU per ml of blood.

Blood Collection Tube Specifications（ml）25
Lithium heparin dosage（IU）3075
Weight of lithium heparin corresponded（mg）0.20.5
Additive volume（ul）2050
Lithium heparin solution concentration（g/l）1010

Lithium Heparin Precautions
When lithium heparin has impurities, foreign matter, abnormal smell, color and expired expiration date, it is forbidden to use

When the lithium heparin solution is cloudy, it may be that the lithium heparin solution has been contaminated or deteriorated. Do not continue to use it.

The preparation of lithium heparin must be prepared in a sterile state, and deionized water is used to ensure the preparation, so as to avoid bacteria growth during the preparation process.

After the lithium heparin solution is added to the blood collection tube, it needs to be sterilized by irradiation. It is recommended to use γ-ray irradiation with a dose of 8-25kGy. The irradiation dose can be determined by the initial number of colonies.

Lithium heparin powder can be stored within the time limit, but after it is configured into a solvent, it needs to be stored at a low temperature of 0-4 degrees, and the storage period should not exceed 7 days. It is recommended to use it now.

This product is not a medicine and cannot be used as an injection. It is forbidden to directly inject it into the human body and animal body.

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