LIPOSOMAL PHOSPHOLIPIDS

(2022年12月09日)

https://www.avt-pharma.com/products/phospholipids-for-liposomes/

Liposomal Phospholipids (used to prepare liposomes) are divided to natural phospholipids and synthetic phospholipids.

AVT, the phosphatidylcholine liposomal manufacturer, is specialized in drug delivery systems such as liposomes, lipid emulsions, and micro-nano targeted formulations.

Our products cover natural phospholipids, synthetic phospholipids, functionalized phospholipids, nucleic acid delivery and other sub-fields.
TYPES OF LIPOSOMAL PHOSPHOLIPIDS (FOR LIPOSOMES)

HSPC/Hydrogenated Soy Phosphatidylcholine Cas 92128 87 5
liposomal Phospholipids are used as skeleton membranes of liposomes.
1,2-Dipalmitoyl-sn-glycero-3-phosphocholine(DPPC)
DPPC is a synthetic phospholipid with a purity of at least 98.0% and can be used as a lipid membrane material in the preparation of liposomes.DPPC is also an endogenous substance and is the main compo...

LIPOSOMAL PHOSPHOLIPIDS (FOR LIPOSOMES) EFFECTS
01
liposomal Phospholipids are used as skeleton membranes of liposomes.

02
liposomal Phospholipids used to prepare liposomes include natural phospholipids and synthetic phospholipids.

03
Synthetic phospholipids are preferred excipients with characteristics of stable properties, anti-oxidation, and stabilizing the finished products.

HOW DO PHOSPHOLIPIDS (FOR LIPOSOMES) WORK?

1. Liposomes are composed of phospholipids as the skeleton membrane and additives. The phospholipids used to prepare liposomes include natural phospholipids and synthetic phospholipids.

2. Additives, such as cholesterol, are needed to prepare liposomes. liposome phospholipid undergoes a mixture with Cholesterol, which is also an amphiphilic substancear, to prepare stable liposomes. Its function is to adjust the fluidity of the bilayer and reduce the liposomes membrane permeability.

3. In the liposome formulation, special excipients are also utilized. For example, irinotecan liposome Onivyde® uses sucrose octasulfate for gradient drug loading.

4.The lyophilized liposome generally uses sucrose or trehalose as the cryoprotectant for lyophilization.

As one of the most professional pharmaceutical excipients manufacturers, we provide liposomal lidocaine injection, liposomal 50 mg injection, excipients in pharmaceutical industry, etc. For more, please feel free to contact us!
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