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https://www.difficultpeptide.com/products/h4k20ac/

H4K20AC
Synthesized histone H4 peptide corresponding to residues within 1-102 of human histone H4 with acetylation K20 modification.

SPECIFICATION OF H4K20AC

CATH4204
Product NameHistone H4-K20ac
Purity≥95% by HPLC analysis
AppearanceWhite powder
UsageResearch use only
StorageShipping at room temperature.
Upon delivery aliquot.
Stored at -20°C or -80°C.
Avoid freeze/thaw cycle.
SequenceSGRGKGGKGL GKGGAKRHRK(ac) VLRDNIQGIT KPAIRRLARR GGVKRISGLI YEETRGVLKV FLENVIRDAV TYTEHAKRKT VTAMDVVYAL KRQGRTLYGF GG

APPLICATION OF H4K20AC
Modification of histones are associated with distinct transcription states and serve as heritable epigenetic markers for chromatin structure and function. H4K20ac is associated with gene repression in human cells. Unlike H3K9me3, a constitutive heterochromatin mark, H4K20ac was less associated with TSSs of completely silenced genes (those with no mRNA expression), suggesting that H4K20ac may play a role in repressing transcribed genes rather than in assisting with heterochromatin formation to induce a fully silent state, possibly preventing methylation on the same residue.

Hefei KS-V Peptide is a pre-clinical new drug research and development CRO company based on structure and chemistry and it has grown into one of the leading and full-fledged peptide manufacturers and peptide suppliers in China. With peptides as the core, it provides innovative peptide and protein products and services for global pharmaceutical companies, biotechnology companies, and scientific research institute.