Widely-Targeted Metabolomics for Plants
(2023年12月05日)https://www.metwarebio.com/plants-widely-targeted-metabolomics-service/
Widely-Targeted Metabolomics for Plants is an innovative metabolomics method that combines the benefits of untargeted metabolomics and targeted metabolomics to achieve high-throughput identification and quantification of a wide variety of metabolites associated with plants. As part of our continual R&D, Metware's plant metabolomics database (MWDB) now houses over 30,000 plant metabolite analysis data to allow more extensive annotation and quantification from plant samples.
Technology Introduction
This methodology is especially useful in plant metabolism research where the number of metabolites far exceeds those in animals. Metware's patented Widely-Targeted Metabolomics approach stands out from many others with features such as:
Using high-resolution mass spectrometers to allow the unbiased collection of MS/MS spectrum data;
Highly curated in-house metabolomics database (MWDB) that provides accurate metabolite identification;
Using MRM analysis from QQQ to accurately quantify metabolites in each sample.
Technical Features of Widely-Targeted Metabolomics for Plants
Large Curated Database
Collected ultra-high sensitivity data of over 30,000 metabolites from over 1000 plant species. Each sample can typically identify 1000-2000 metabolites.
Rigorous Quality Control
A mature quality control system monitoring all aspects of experimentation from sample preparation to data collection.
Experienced
Stable and tested sample preparation protocol stemming from processing over 1 million samples a year. Over 10 different plant tissues from 1000 plant species has been processed through our lab.
Accurate Identification
Combining AB SCIEX QTOF 6600+ ultra-high resolution mass specltrum with our in-house curated database to achieve accurate metabolite identification.
Accurate Quantification
Using MRM mode from AB SCIEX Triple Quad 6500+ to achieve accurate relative quantification of metabolites.
Publication Tested Results
Results of our services have been cited in over 500 publications with a combined lF over 3000.
Applications of Widely-Targeted Metabolomics for Plants
Applications: Research In Plant Development
Applicable for identifying metabolic changes in different stages of plant growth such as seed germination, stem elongation, flower development, pollination, and fruit development.
Article Spotlight: MicroTom Metabolic Network: Rewiring Tomato Metabolic Regulatory Network throughout the Growth Cycle
This study integrated high-resolution Spatio-temporal metabolome and transcriptome data to systematically explore the metabolic landscape across 20 major tomato tissues and growth stages. Based on their MicroTom Metabolic Network, they divided 540 detected metabolites and their co-expressed genes into 10 distinct clusters based on their biological functions. This enabled them to construct a global map of the major metabolic changes that occur throughout the tomato growth cycle and dissected the underlying regulatory network. Furthermore, they identified novel transcription factors that regulate the biosynthesis of important secondary metabolites such as steroidal glycoalkaloids and flavonoids.
If you want to know more about plant metabolite detection and plant metabolite quantification, please visit our website.
Metware library is propelling discoveries and transforming industries in life science, biotech, and pharmaceutical research and development. A partnership with Metware Biotechnology goes beyond data and reports. Our specialists accompanies you from design to discovery. Contact us to see how we can be a part of your solution.
- このできごとのURL:
コメント