年表作成・共有サービス - pastport

https://www.metwarebio.com/tm-widely-targeted-metabolomics-service/

TM Widely-mass spec metabolomics is the 'Untargeted metabolomics + Targeted Metabolomics' process that achieves the perfect combination of high resolution, wide-coverage, high sensitivity, and precise quantification. It is a great starting point to examine the global metabolite profile. Metware's curated database of 280,000 metabolites, which includes 3000 metabolites not found in public databases, allows more annotations from high-resolution mass spec data.

Technology Introduction
"TM" Widely-mass spectrometry for metabolomics combines Untargeted metabolomics and Targeted metabolomics to achieve the perfect combination of high-resolution, wide-coverage, high-sensitivity, and precise quantification. Metware's patented Widely-Targeted Metabolomics technology stands out from many others with features such as:

Using high-resolution mass spectrometers to allow the unbiased collection of MS/MS spectrum data;

Highly curated metabolomics database with over 7000+ in-house metabolite database providing more metabolite annotation;

Using MRM analysis from QQQ to accurately quantify metabolites in each sample.

Technical Features of TM Widely-Targeted Matabolomics Service

Large Curated Database
Collected ultra-high resolution data of over 280,000 metabolites. Each sample can typically identify over 1300 metabolites.

Rigorous Quality Control
A mature quality control system monitoring all aspects of experimentation from sample preparetion to data analysis.

Experienced
Stable and tested sample preparation protocol stemming from processing over a million samples a year.

Accurate Identification
Combining AB SCIEX QTOF 6600+ ultra-high resolution mass spectrum with our large curated database to achieve accurate metabolite identification.

Accurate Quantification
Using MRM mode from AB SCIEX Triple Quad 6500+ to achieve accurate relative quantification of metabolites.

Applications of TM Widely-Targeted Matabolomics Service
Clinical marker discovery and development

Understanding mechanisms behind disease progression

Studying drug efficacy and toxicity

Environmental toxicology research

SERVICES
Global Metabolite Profiling

Untargeted Metabolomics
TM Widely-Targeted Metabolomics
Widely-Targeted Metabolomics for Plants
Flavonoids Metabolomics
Targeted Metabolomics

Lipidomics

Multi-Omics

List of Metabolites
Our curated database contains over 280,000 metabolites. Our in-house standard database has over 3,000 metabolites. The integrated public database has over 150,000 metabolites, and the AI predictive structural database has over 130,000 metabolites. The integrated public databases include KEGG, HMDB, Metlin, Mass Bank, Lipid Search, and other commonly used databases.

The in-house standard database contains 3000 metabolites as shown below:

CategoryQuantityRepresentative substance
Amino acids and their metabolites600+Glycine, L-threonine, L-arginine, N-acetyl-L-alanine
Organic acids and their derivatives400+3-hydroxybutyric acid, adipic acid, hippuric acid, kynurenine
Nucleotides and their metabolites200+Adenine, 5'-Adenine Nucleotide, Guanine, 2'-Deoxycytidine
Carbohydrates and their metabolites100+D-glucose, glucosamine, D-fructose 6-phosphate
Lipid500+O-acetylcarnitine, γ-linolenic acid, lysophosphatidylcholine 22:4
Benzene and its derivatives500+Benzoic acid, 3,4-dimethoxyphenylacetic acid, 4-hydroxybenzoic acid
Coenzymes and vitamins60+Folic acid, pantothenic acid, vitamin D3
Alcohols, amines150+Dopamine, histamine, DL-1-amino-2-propanol
Aldehydes, ketones, esters120+Furfural, ethyl butyrate, α-pentyl cinnamaldehyde
Heterocyclic compound200+Pyridoxal, biopterin, indole-3-acetic acid
bile acid40+Glycocholic acid, deoxycholic acid, taurolithocholic acid
Hormones and hormone-related substances100+Juvenile hormone 3, epinephrine, 3,3'-diiodo-L-thyroxine
Tryptamine, choline, pigment15+Serotonin, bilirubin (E-E), urobilin
other50+Astaxanthin, hydroxyurea
total3000+

Analysis Content Display of Untargeted Metabolomics Service
Our complete service includes various data analyses to jump start your research. Below are a few components that you may find in our data analysis report.

There are many metabolomics service providers, but we are one of the best choices for you.