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The Beneficial Effects Of Stem Cell Therapy in Cardiovascular Diseases
Stem cell transplantation can regenerate the myocardium and improve cardiac function and is an ideal choice for the treatment of acute myocardial infarction, ischemic heart disease, ischemia-reperfusion injury of the heart, and other cardiovascular diseases. At SQ1 medical center, we provide you with a customized stem cell therapy plan, after the treatment course and cooperating with the doctor’s diet plan and lifestyle advice, 83% of the patients reported significant treatment effects, and the related symptoms are greatly improved.
Cardiac stem cells therapy at SQ1 helps:
Reduce fibrosis

Deep vein thrombosis

Cardiovascular Diseases That Stem Cell Therapy Can Treat
On November 13-15,2021, the 2021 American Heart Association Annual Conference was held online, and reported the latest results of the clinical result of the largest stem cell therapy for heart failure (DREAM-HF trial): stem cell therapy can significantly reduce the risk of heart attack, stroke, and death in patients with chronic, high-risk, reduced ejection fraction heart failure (HFrEF), especially those with higher levels of inflammation.

Learn More About Cardiovascular Diseases
Cardiovascular diseases generally refer to cardiovascular and cerebrovascular diseases, which is the general term for ischemic or bleeding diseases of the heart, brain, and other tissues over the body caused by hyperlipidemia, blood viscosity, atherosclerosis, hypertension, etc. In recent years, due to the improvement in living quality and changes in dietary structure, the incidence of cardiovascular disease is increasing, which seriously threatens human health.
Cardiomyocytes will be lost permanently after necrosis; The irreversible death of cardiomyocytes is one of the most important factors in the onset of heart diseases such as myocardial infarction and heart failure. Due to the limited regeneration capacity of cardiomyocytes, cardiovascular disease has become the “No.1 Killer” that threatens human health. The number of morbidity and mortality is increasing each year. Cardiovascular disease has become a major global public health issue.

Risk Factors For Cardiovascular Diseases

Cardiovascular diseases can be roughly divided into two categories: congenital and acquired diseases. Congenital factors include family inheritance or self-gene mutation, acquired factors are unhealthy lifestyle, other related diseases, and adverse drug reactions. The onset of the disease is often affected by a combination of factors.

However, stem cell transplantation can overcome those drawbacks. Compared with conventional therapy, stem cell therapy has incomparable advantages：

Advantages Of Stem Cell Treatment For Cardiovascular Diseases
Stem cell therapy
Conventional treatment
Curative Treatment or diseases management
Stem cell therapy is a new treatment for cardiovascular diseases, which aims to repair or regenerate damaged myocardial tissue, promote angiogenesis, and thus help the heart return to a healthy status and rebuild cardiac function.

If treated with stem cells at an early stage, damage to cardiac cells can be reversed. Stem cell therapy can also free you from drug dependence and surgery.

Conventional treatments for early-stage cardiovascular diseases include drug therapy and interventional therapy, both of which can only relieve some related symptoms, such as decreasing blood sugar/blood pressure, and reducing chest tightness, but cannot completely cure cardiovascular diseases.

Cardiomyocyte loss is irreversible, and cardiovascular disease caused by myocardial damage is considered incurable in conventional medicine.

Dosage
When stem cells repair damaged myocardial tissue and blood vessels, you will gradually restore normal heart function, and the dosage of drugs you are taking can be gradually reduced, and even interventional treatment can be avoided. Drug dependence can be completely reversed if treated with stem cells at an early stage.

Stem cell experts based on your current level of disease and other comorbidities will design a customized protocol and decide, the number of stem cells, source of stem cells, and cycles of stem cell therapy.

If you choose drug therapy for cardiovascular disease, you may find the dose of the medications is gradually increased, or you need to take the medications for life.

When drug treatment fails to control the progress of the disease condition, you may need to choose interventional treatment, but this is not a one-time-for-all solution, you need regular follow-up and may even need another interventional treatment.

Side-effects
No Side-effects as stem cells are our cells that are used to treat the disease and regenerate lung tissue to regain proper functioning.

Medications may have side effects on the digestive and nervous system, such as dry cough, edema, dizziness, headache, nausea, allergic reactions, etc.

Convenience
Stem cell therapy is performed by stem cell specialists which requires a special laboratory to process the stem cells and the medical set-up to extract and inject the stem cell.

The therapy is going to be injection-based and needs to be performed in a hospital.

It’s relatively easy to take medications, but the patient needs to take them repeatedly every day, which is prone to the development of drug dependence.

If you choose interventional or surgical treatment, the patient needs to be hospitalized for surgery, which is not ideal due to the trauma and high risk from the surgery.

Longevity
If treated in the early stage, in the long run, stem cell therapy can eliminate drug dependence, restore cardiovascular function (as all related clinical measurements return to normal), and return the patient to a healthy life. If conducted at a later stage, stem cell therapy can still reduce drug dependence, and in rare cases, you might need several treatment regimens. The endothelial stem cells we use improve the condition of not only the heart muscle, but also the coronary vessels.

The effect of drug therapy is short-term, and patients need to take medications daily, once stopped, the symptoms will resume or even worsen.

Interventional therapy is a one-time therapy, but if there is a recurrence or other unexpected conditions, another interventional therapy is needed, and its effect is not guaranteed for a lifetime.

End-stage
Stem cells are the fundamental part of our body, the main function of stem cells is to regenerate and repair damaged cells, produce new body cells thus repair and regenerate myocardial tissue thus delaying or avoiding the necessity to conduct kidney transplantation surgery.

Heart transplantation is the only treatment option for end-stage patients. Heart transplantation surgery is highly sophisticated with the risk of infections and rejection reactions. At the same time, limited donors, and high costs are important concerning factors for receiving heart transplantation.

How Can Stem Cell Therapy For Cardiovascular Diseases Work

Multidirectional differentiation into cardiomyocytes: In the myocardial microenvironment, the transplanted stem cells can differentiate into cardiomyocytes expressing myocardial-specific genes. This increases the number of cardiomyocytes, therefore improving the ejection function of the heart.

Multidirectional differentiation into vascular endothelial cells: Stem cells can be directly induced to differentiate into vascular endothelial cells by inducers such as vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), insulin-like growth factor (IGF), epidermal growth factor (EGF), ascorbic acid and heparin. This effect will promote the formation of new blood vessels.

Anti-inflammation and anti-fibrosis: After the stem cells are infused back into the body, on one hand, they will inhibit the release of inflammatory factors, and inhibit inflammatory reactions in the cardiovascular system on time. On the other hand, the stem cells pretreated with endothelin-1 can enhance the anti-fibrotic function of the myocadiac tissue. In addition, scientific research has shown that stem cells have significant effects in improving cardiac function and reducing fibrosis by expressing hepatocyte growth factor (HGF).

Immunomodulatory effect: stem cell medicine immune regulation includes paracrine and immune cell regulation mechanisms. Various soluble factors produced and secreted by mesenchymal stem cells play an important role in immune regulation. For example, NO can not only inhibit the growth of T cells but also regulate immune cells by up-regulation of inducible nitric oxide synthase(iNOS). The immune regulatory effect of mesenchymal stem cells is exerted through immune suppression the proliferation and maturation of immune cells

If you want to know more details of stem cell therapy heart failure, please visit our website.

More uses of stem cells in medicine, please contact us.